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(Chest. 1972;61:683-685.)
© 1972 American College of Chest Physicians

Sinoatrial Arrest due to Lidocaine in a Patient Receiving Quinidine

Robert M. Jeresaty M.D.1; Abdul H. Kahn M.D.2; and Arthur B. Landry Jr. M.D., F.C.C.P.3

1 Director, Section of Cardiology; Assistant Professor of Medicine and Consultant in Cardiology, University of Connecticut School of Medicine
2 St. Francis Hospital, Hartford, Connecticut
3 Director, ECG Laboratory; Assistant Professor of Medicine, University of Connecticut School of Medicine and Yale University School of Medicine

A patient with sinoatrial arrest and atrioventricular junctional escape rhythm due to lidocaine is reported. The patient was on small doses of quinidine. Two other cases of sinoatrial arrest associated with lidocaine infusion have been reported in the literature. In these three cases, sinus arrest occurred under one of the three following conditions: 1) advanced age, 2) probable interaction with other drugs (quinidine and phenylhydantoin), 3) inferior wall myocardial infarction.






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Copyright © 1972 by the American College of Chest Physicians.