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(Chest. 1972;62:251-253.)
© 1972 American College of Chest Physicians

Carcinoma of the Lung and Anthracosilicosis

Domenico Scarano M.D.1; A. Moneim A. Fadali M.D., F.C.C.P.1; and Gerald M. Lemole M.D., F.C.C.P.1

1 Department of Thoracic Surgery, Veterans Administration Hospital, Wilkes-Barre, Pennsylvania; Department of Cardiothoracic Surgery, Temple University Health Sciences Center, Philadelphia

This study reviews 11 years' experience with carcinoma of the lung in relation to anthracosilicosis at the Veterans Administration Hospital, Wilkes-Barre. Carcinoma of the lung was diagnosed in 7 percent of 2,360 anthracosilicotics compared to 1.08 percent in 31,187 nonanthracosilicotics. Epidermoid carcinoma was the predominant cell type encountered in the anthracosilicotics, but anaplastic carcinoma and adenocarcinoma were not. The possible role of immunologic factors, chronic microtrauma by the silica particles and uranium radioactivity in the pathogenesis of bronchogenic carcinoma in these cases is discussed. The difficulties in diagnosis are mentioned and in particular, the lower operability and resectability rates of carcinoma in this group is emphasized.






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Copyright © 1972 by the American College of Chest Physicians.