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(Chest. 1972;62:400-402.)
© 1972 American College of Chest Physicians

Granular Pneumocyte and Pulmonary Fibrosis

Fumi Watanabe M.D.1; Marcia M. Mitchell M.D., F.C.C.P.1; and Attilio D. Renzetti Jr. M.D.1

1 Pulmonary Disease Division of the Department of Medicine, University of Utah College of Medicine; and Veterans Administration Hospital, Salt Lake City

Electron microscopic study of lung tissue in the state of fibrosis from desquamative interestitial pneumonia, idiopathic hemosiderosis and diffuse interstitial fibrosis of unknown etiology demonstrated the abundant presence of acanthosomes in granular pneumocytes which were adjacent to developing elastin fibers or collagen. By analogy with similar observations in fibroblasts, it is suggested that the granular pneumocyte may be important to the process of repair in the lung.






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Copyright © 1972 by the American College of Chest Physicians.