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(Chest. 1972;62:86S-94S.)
© 1972 American College of Chest Physicians

Positive End-Expiratory Pressure (PEEP); Indications and Physiologic Considerations

Harvey J. Sugerman M.D.1; Robert M. Rogers M.D., F.C.C.P.2; and Leonard D. Miller M.D.3

1 Instructor in Surgery, University of Pennsylvania School of Medicine
2 Professor of Medicine; Associate Professor of Physiology and Chief, Pulmonary Disease Section, University of Oklahoma Medical Center, Oklahoma City, Oklahoma
3 Professor of Surgery, University of Pennsylvania School of Medicine

PEEP is an important therapeutic tool for treating patients with the respiratory distress syndrome of adults. It reverses the severe hypoxemia, large (A-a) O2 gradient, decreased functional residual capacity and compliance immediately. It also seems to produce a more gradual improvement in oxygenation over 12-48 hours. Currently, it has been used only for patients with RDSA and does not appear to be indicated for other lung diseases.






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Copyright © 1972 by the American College of Chest Physicians.