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1 Mayo Clinic and Mayo Foundation, Rochester, Minnesota
A patient is described in whom pulmonary asbestosis was proved by open-lung biopsy. In the specimens examined, extensive inflammatory and fibrotic changes were present and fermginous bodies were demonstrated by iron stains. Characteristic reduction in lung volumes and diffusing capacity were improved by avoidance of exposure to asbestos, most probably because of reversibility of inflammatory changes in alveoli. Within the,limits of the sampling method, eleclron microscopy showed that the disease involved principally alveolar septal interstitiurn. The appearance of the surviving blood-air barriers was normal.
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