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(Chest. 1973;63:348-352.)
© 1973 American College of Chest Physicians

Clinical Evaluation of Stabilized and Nonstabilized PPD-B in Patients with Group III Atypical Mycobacteria

Michael B. Zack M.D.; Lynn L. Fulkerson M.D., F.C.C.P.1; Gail Hartshorne B.S., R.N.2; Elgin Kennedy M.D.3; and Emunuel Stein M.D., F.C.C.P.4

1 Associate Chief, Department of Medicine, US Public Health Service Hospital, Staten Island
2 Public Health Nurse Coordinator, USPHS Hospital, Staten Island
3 General Medical Officer, US Public Health Service Hospital, Staten Island
4 Chief, Medical Education and Clinical Cardiology, US Public Health Service Hospital, Staten Island

Fifty-five individuals with positive cultures for nonchromogenic group III atypical mycobacteria were skin tested. PPD-B and PPD-B stabilized with Tween 80 to prevent glass adhesion were compared. In addition PPD-B and PPD were compared using both stabilized and nonstabilized preparations. Stabilized PPD-B was much more sensitive than nonstabilized PPD-B and there were far fewer false negatives. In this population the dual skin test procedure was of no diagnostic benefit. The results support the conclusion that enhanced biologic accuracy in a clinical setting is obtainable with stabilized intermediate strength tuberculin PPD-B.






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Copyright © 1973 by the American College of Chest Physicians.