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(Chest. 1973;63:409-412.)
© 1973 American College of Chest Physicians

Quantitative Relation between Coronary Atherosclerosis and Blood Lipids

Cyrus Farrehi M.D.1; Anne M. Perley M.A.2; Manuel Malinow M.D., F.C.C.P.3; and Melvin P. Judkins M.D.4

1 Assistant Professor of Medicine, University of Oregon Medical School; Chairman, Department of Medicine, McLaren Hospital, Flint, Michigan
2 Division of Cardiology, Department of Medicine, Department of Radiology, University of Oregon Medical School, Veterans Administration Hospital and the Oregon Regional Primate Research Center, Portland
3 Associate Professor of Medicine; Chairman, Division of Cardiovascular Physiology, Oregon Regional Primate Research Center
4 Professor of Diagnostic Radiology and Director of Cardiovascular Radiology Laboratory

Fasting and postprandial blood triglycerides and cholesterol were measured in 38 patients in whom the extent of coronary atherosclerosis was assessed by selective arteriography. A significant correlation was found between fasting and postprandial triglycerides and the severity of coronary atherosclerosis. When nine subjects with diminished glucose tolerance were eliminated, the cholesterol levels also showed a significant correlation with the severity of atherosclerosis. The findings support the quantitative relationship between these blood lipids and coronary atherosclerosis.






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Copyright © 1973 by the American College of Chest Physicians.