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(Chest. 1973;63:638-641.)
© 1973 American College of Chest Physicians

Bronchopleurocutaneous Fistula Due to Infection with Histoplasma Capsulatum

Leo E. Johns Jr. M.D., F.C.C.P.1; Robert G. Garrison Ph.D.1; and Thomas G. White Ph.D.1

1 Department of Medicine and the Research Laboratory, Veterans Administration Hospital, Kansas City, Missouri; Departments of Medicine and Microbiology, University of Kansas Medical Center, Kansas City, Kansas; Department of Microbiology, University of Missouri Kansas City School of Dentistry

We report the case of a patient admitted with a draining sinus tract of the chest wall, which was shown to be a bronchopleurocutaneous fistula. Numerous colonies of both albino and brown filamentous Histoplasma capsulatum were demoustrated subseaquently from both sputum and sinus tract drainage material. Exhaustive cultural procedures were negative in an attempt to establish an etiologic relationship of the fistula with other bacterial or fungal organisms. Therapy was instituted with intravenous amphotericin B followed by subsidence of symptoms and healing of the fistulous tract. We believe this to be the first case report of pulmonary histoplasmosis presenting this manner.




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