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(Chest. 1973;63:11S-11S.)
© 1973 American College of Chest Physicians

Vagally-Mediated Reflex Bronchoconstriction in Allergic Asthma

Warren M. Gold M.D.1

1 University of California San Francisco Medical Center

Our results cannot be explained by the classic theory of asthma and we believe that this theory must be modified. Although some direct, local constriction of airway smooth muscle may occur, a major component of the acute bronchoconstrictor response to antigen inhalation appears to involve a vagally-mediated reflex, possibly arising from epithelial irritant receptors in the airways.






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Copyright © 1973 by the American College of Chest Physicians.