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1 University of Oregon Medical School, Portland
Lung lavage with heparin-saline solution in the treatment of a patient with pulmonary alveolar proteinosis was no better than lavage with saline alone. Sufficient heparin was absorbed from the lung so that the patient's clotting time was prolonged and he sustained a retroperitoneal bleed. We believe clinicians should be alert to the possibility of heparin absorption from the lung, especially when large doses are used during lung lavage.
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J. F. Seymour and J. J. Presneill Pulmonary Alveolar Proteinosis: Progress in the First 44 Years Am. J. Respir. Crit. Care Med., July 15, 2002; 166(2): 215 - 235. [Abstract] [Full Text] [PDF] |
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