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1 Department of Radiology and the Department of Medicine, Pulmonary Disease Section, University of Utah Medical Center, Salt Lake City, Utah
Two patients with chronic sarcoidosis developed marked stenosis and obstruction of the segmental bronchial orifices. Bronchoscopy and radiographic studies suggested that the bronchi were involved by extensive peribronchial fibrosis in the central portions of the lungs. In one patient, the bronchial narrowing showed no change over a seven-year period, despite improvement of the pulmonary involvement following corticosteroid and chlorambucil therapy. The bronchial Narrowing is probably due to granulomatous involvement of the bronchial walls with subsequent scarring and stenosis.
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