Concurrent Intrathoracic Hodgkin's Disease and Hypertrophic Osteoarthropathy

¹ Division of Rheumatology, Department of Medicine, University of California San Diego, La Jolla
² Professor of Medicine and Acting Chairman, Department of Medicine

Three patients who manifest intrathoracic Hodgkin's disease and concurrent hypertrophic osteoarthropathy (HOA) are presented and compared with four similar patients previously noted in the literature. All were childen or young adults. The clinical, roentgenographic and pathologic features of HOA as seen in these patients are similar to the more familiar syndrome appearing in adults. Although periosteal reaction may occur in Hodgkin's disease of bone, it almost never appears without destruction of the underlying cortical bone; thus, differentiation between Hodgkin's disease of bone and HOA need not be difficult.