Chest ACCP Education Calendar
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Guest Access | Sign In via User Name/Password
This Article
Right arrow Full Text (PDF) Free
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Article Archive
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Rubin, A. E.
Right arrow Articles by Bruderman, I.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Rubin, A. E.
Right arrow Articles by Bruderman, I.
(Chest. 1973;63:948-951.)
© 1973 American College of Chest Physicians

Overdistension of Lung Due to Peripheral Airways Obstruction

A. E. Rubin M.D.1 and Israel Bruderman M.D., F.C.C.P.1

1 Department of Chest Diseases and Pulmonary Research Laboratory, Meir Hospital, Kfar-Saba, and Tel-Aviv University School of Medicine, Israel.

A group of seven "normal" young adults who complained of dyspnea during exercise only, and who were nonsmokers with no previous history of pulmonary disease, were studied. No abnormal physical findings or chest x-ray abnormalities were present. All showed an increased residual volume and functional residual capacity in the presence of normal total lung resistance and forced expiratory volume in the 1st second. A decrease in dynamic compliance up to 64 percent mean value of the static compliance (range 48 percent to 78 percent) at a respiratory frequency of 90 breaths per minute was found which indicated airway obstruction of the peripheral bronchioles. In a control group of five normal subjects no decrease in frequency dependent compliance occurred. Combined antibiotic and bronchoditor treatment reversed the functional abnormalities in only one out of the seven patients. In these patients the overdistension of the lung is the result of small airways obstruction. The cause of small airways disease is assumed to be either an inflammatory process, allergic reaction or both.




This article has been cited by other articles:


Home page
 ChestHome page
D. Stanescu
Small Airways Obstruction Syndrome
Chest, July 1, 1999; 116(1): 231 - 233.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1973 by the American College of Chest Physicians.