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1 Hypertension Division, Department of Medicine, The University of Oklahoma health Sciences Center, Oklahoma City, Okla
The basic hemodynamic principles applicable to the control of arterial pressure have been reviewed in the light of recently reported observations in a variety of the hypertensive diseases. These findings include the description of pathophysiological alterations associated with the development of essential hypertension, hypertensive heart disease and renovascular hypertension. Utilizing these physiological concepts, a rational basis for modern antihypertensive therapy is suggested.
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