Chest ACCP Career Connection
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Guest Access | Sign In via User Name/Password
This Article
Right arrow Full Text (PDF) Free
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Article Archive
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Patchefsky, A. S.
Right arrow Articles by Lipshitz, H. I.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Patchefsky, A. S.
Right arrow Articles by Lipshitz, H. I.
(Chest. 1973;64:459-464.)
© 1973 American College of Chest Physicians

Interstitial Pulmonary Fibrosis and von Recklinghausen's Disease. An Ultrastructural and Immunofluorescent Study

Arthur S. Patchefsky M.D.1; William G. Atkinson M.D.1; Willis S. Hoch M.D.1; Gloria Gordon B.S.1; and Herman I. Lipshitz M.D.1

1 Thomas Jefferson University Hospital, Philadelphia, Pa.

We present the clinical and pathologic findings in a 28-year-old white woman with pulmonary fibrosis and von Recklinghausen's disease. Ultrastructural examination of a lung biopsy specimen showed increased collagen in the alveolar wall, associated with hyperplasia of granular pneumocytes. Large numbers of intraalveolar cells, morphologically suggestive of macrophages, but having tight junctions similar to epithelial cells were also present. Direct immunofluorescent examination using goat anti IgG, IgM, IgA, compliment, albumin, and fibrinogen failed to show specific fluorescence. Despite certain structural similarities to other familial and idiopathic forms of interstitial pneumonja, the pathogenesis remains poorly understood.

Submitted on March 2, 1973
Accepted on April 3, 1973




This article has been cited by other articles:


Home page
 ChestHome page
J. H. Ryu, J. G. Parambil, P. S. McGrann, and G. L. Aughenbaugh
Lack of Evidence for an Association Between Neurofibromatosis and Pulmonary Fibrosis
Chest, October 1, 2005; 128(4): 2381 - 2386.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1973 by the American College of Chest Physicians.