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(Chest. 1974;65:148-151.)
© 1974 American College of Chest Physicians

The High Incidence of Pulmonary Functional Abnormalities in Patients with Coronary Artery Disease

Bruce J. Sobol M.D., F.C.C.P.1; Walter H. Herbert M.D.2; and C. Emirgil M.D., F.C.C.P.1

1 The Cardiopulmonary Laboratory, Grasslands Hospital, Valhalla, N.Y.; Department of Medicien, New York Medical College, New York, N.Y.
2 The Cardiopulmonary Laboratory, Grasslands Hospital, Valhalla, N.Y. and the Department of Medicien, New York Medical College, New York, N.Y.

Ventilatory function was studied in 51 subjects undergoing coronary arteriography because of known or suspected coronary artery disease. All subjects were free of systemic hypertension or other forms of heart disease and none was in congestive heart failure. Sixty percent of those with objective evidence of coronary artery disease and/or left ventricular dysfunction had at least one abnonmality of ventilatory function. Pulmonary functional abnormalities were not clearly related to the number of objective abnormalities, but the number of subjects was small. There was no relationship between the severity of left ventricular diastolic elevation and ventilatory abnormalities. On the other hand, the five subjects who did not smoke cigarettes had no pulmonary abnormalities and this incidence is statistically significantly different from the remaining 46 subjects. This emphasizes that any study attempting to relate the ventilatory effects of coronary heart disease must consider the common factor in both—cigarette smoking. Abnormal pulmonary function and heart disease have cigarette smoking as a common etiologic base rather than pulmonary abnormalities occurring as a consequence of heart disease.

Submitted on January 19, 1973
Accepted on September 10, 1974




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