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1 Research and Development Center, Thermo Electron Corporation, Waltham, Mass., and the Cardiovascular Division, Sears Surgical Research Laboratories, Harvard Medical School, Boston, Massachusetts
2 Cardiovascular Surgical Research Laboratories, Texas Heart Institute of St. Luke's Episcopal and Texas Children's Hospitals, Houston, Texas
Nuclear-fueled cardiac pacemakers have reached the stage of clinical evaluation. Approximately 600 units have been implanted in patients. Such pacemakers have the potential of long life. Studies on animals indicate that the somatic and genetic effects from such sealed sources do not preclude clinical use. In our institutions, third-party insurance carriers have assumed their cost. The primary problem is the maintenance of fuel capsule integrity under all creditable conditions.
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