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(Chest. 1974;65:684-687.)
© 1974 American College of Chest Physicians

Sarcoidosis: The Significance of an Acinar Pattern on Chest Roentgenogram

Steven A. Sahn M.D.1; Marvin I. Schwarz M.D., F.C.C.P.2; and S. Lakshminarayan M.D.3

1 Instructor, Department of Medicine, Division of Pulmonary Disease
2 Chief, Pulmonary Diseases, General Rose Memorial Hospital and Assistant Professor of Medicine, Division of Pulmonary Disease
3 Assistant Professor of Medicine, Division of Pulmonary Diseases

A young black woman presented with dyspnea on exertion and a productive cough. The chest roentgenogram showed predominance of an acinar rosette pattern without hilar adenopathy. Lung biopsy showed multiple non-caseating granulomata in the interstitium, compatible with the diagnosis of sarcoidosis, with alveoli filled with mononuclear cells. The term alveolar sarcoidosis is a radiologic diagnosis based on certain proposed criteria for acinar filling. Supported by pathologic correlation, it appears that the acinar radiographic pattern may represent a secondary nonspecific response of the lung to the primary interstitial injury.






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Copyright © 1974 by the American College of Chest Physicians.