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1 Assistant Resident, Department of Pathology, The Johns Hopkins Hospital
Seven of 37 patients with cryptococcosis examined at autopsy had anatomic evidence of pleural cryptococcal infection and effusion. An immediately subpleural nodule which had extended to involve the pleura was identified in six cases. These observations suggest that pleural involvement with effusion is more common than generally appreciated. Pleural infection may be an indication of reduced host resistance, since it appears to result from spread from a subpleural nodule, the presumed primary site of pulmonary cryptococcal infection.
Submitted on January 18, 1974
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