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(Chest. 1974;66:197-199.)
© 1974 American College of Chest Physicians

Fatal Adenovirus Pneumonia in a Young Adult Associated with ADV-7 Vaccine Administered 15 Days Earlier

E. F. Loker Jr. M.D.1; G. R. Hodges M.D.1; and D. J. Kelly M.D.2

1 Department of Medicine, Naval Hospital, Great Lakes, Illinois
2 The Laboratory Service, Naval Hospital, Great Lakes, Illinois

A 19-year-old man presented with mild respiratory distress and bilateral interstitial infiltrates on chest roentgenogram. Progressive, ultimately fatal, respiratory failure ensued. Although he had received adenovirus (ADV) 4 and 7 oral vaccine, the etiology was most likely ADV-7. To our knowledge, this is the first reported case of fulminant ADV-7 pneumonitis associated with prior administration of ADV-7 vaccine.






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Copyright © 1974 by the American College of Chest Physicians.