Myocardial Sarcoidosis Presenting as Acute Mitral Insufficiency

¹ Associate Professor of Medicine; Head, Division of Cardiology
² Assistant Professor of Medicine and Physician-in-Charge, Cardiac Catheterization Unit
³ Departments of Medicine and Pathology, Division of Cardiology, Queens Hospital Center, Long Island Jewish-Hillside Medical Center Affiliation, Clinical Campus of the School of Medicine, State University of New York, Medical School at Stony Brook, Stony Brook, NY.
⁴ Associate Professor of Pathology, Associate Director, Department of Pathology

A young patient with acute mitral insufficiency with a rapid and fatal course is presented. On autopsy, diffuse sarcoid granulomatous infiltration was found in the anterior and posterior walls of the left ventricle, in the interventricular septum and in both papillary muscles. Sarcoidosis as a cause of valvular involvement should be considered in patients with the sudden appearance of mitral incompetence, conduction defects and arrhythmias.