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Chest, Vol 67, 123-125, Copyright © 1975 by American College of Chest Physicians

ARTICLES

Hyperventilation-induced T-wave changes in the limb lead electrocardiogram

GS Golden, LH Golden and FR Beerel

Seventy-two healthy young individuals were subjected to controlled, moderate hyperventilation with room air and with 4.9 percent CO2 in air, and monitored electrocardiographically. Significant summed frontal T-wave changes with hyperventilation (sigmaT1,2,3 larger than or equal to 1.5 mm) were observed in 12 patients. Six subjects (8.3 percent) showed T-wave depression. It was reversed in five patients by hyperventilation with 4.9 percent CO2 in air. T-wave elevation, observed in six subjects, was reversed in four patients by hyperventilation with 4.9 percent CO2. A short period of hyperventilation with an air mixture containing 4-5 percent CO2 is suggested as a means of screening patients under suspicion of ischemic heart disease exclusively on the basis of ECG changes.


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J. J. Rutherford, T. H. Clutton-Brock, and M. J. Parkes
Hypocapnia reduces the T wave of the electrocardiogram in normal human subjects
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[Abstract] [Full Text] [PDF]


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Copyright © 1975 by the American College of Chest Physicians.