Chest ACCP Education Calendar
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Guest Access | Sign In via User Name/Password
This Article
Right arrow Full Text (PDF) Free
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Article Archive
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Taeusch, W.
Right arrow Articles by Avery, M. E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Taeusch, W., Jr.
Right arrow Articles by Avery, M. E.
(Chest. 1975;67:49S-50S.)
© 1975 American College of Chest Physicians

Pharmacologic Regulation of Alveolar Surfactant in Fetal and Newborn Rabbits

ACTH Heroin, Isoxsuprine, and Glucocorticoid

William Taeusch Jr. M.D.1; Issie Wyszogrodski Ph.D.1; Andrew Bator A.B.1; Marie Robert A.B.1; Stephen Carson A.B.1; and Mary Ellen Avery M.D.1

1 Departments of Pediatrics and Physiology, McGill University, McGill University-Montreal Children's Hospital Research Institute, Montreal, Canada

The evidence that pharmacologic doses of glucocorticoids induce lung maturation and diminish risk of respiratory distress syndrome has been reviewed briefly. Studies with heroin corroborate that pharmacologic induction of lung maturation is possible in the human fetus. Endogenous fetal glucocorticoids may serve as a physiologic mechanism that prepares the immature lungs for birth. Catecholamines may induce release of stored surfactant from type 2 cells into alveolar spaces.






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1975 by the American College of Chest Physicians.