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Chest, Vol 68, 824-826, Copyright © 1975 by American College of Chest Physicians

ARTICLES

Pulmonary talc embolization

G Marschke, L Haber and M Feinberg

A young woman with a history of drug abuse rapidly developed cor pulmonale, restrictive pulmonary defect, low diffusion capacity, and a suggestion of left ventricular dysfunction. She died from complications after a lung biopsy. Microscopic examination showed talc granulomas and arteritis. Some form of closed biopsy is probably safer, and trial of corticosteroid therapy seems warranted for this diagnosis. Talc ia a dangerous ingredient for any oral preparation that is likely to be used parenterally.


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Copyright © 1975 by the American College of Chest Physicians.