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Chest, Vol 72, 166-169, Copyright © 1977 by American College of Chest Physicians


ARTICLES

Desquamative interstitial pneumonia-like reaction accompanying pulmonary lesions

CW Bedrossian, C Kuhn 3d, MA Luna, RH Conklin, RB Byrd and PD Kaplan

Six patients with specific pulmonary diseases had pulmonary tissue surgically resected for diagnostic purposes. All six cases were characterized by space-occupying lesions surrounded by a peculiar reaction of the pulmonary parenchyma indistinguishable from desquamative interstitial pneumonia. If small biopsies from these areas had been taken, a diagnosis of desquamative interstitial pneumonia would have been made, and the underlying process would have gone undetected. These cases corroborate even further the concept that desquamative interstitial pneumonia is a pattern of pulmonary reaction, rather than a well-defined disease entity. Furthermore, it seems advisable to make the dianosis of desquamative interstitial pneumonia only when other conditions have been carefully ruled out by thorough clinical and pathologic investigations.


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