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Chest, Vol 73, 173-178, Copyright © 1978 by American College of Chest Physicians


ARTICLES

The management of acute quinidine intoxication

C Shub, GT Gau, PM Sidell and LA Brennan Jr

A 16-year-old patient survived severe intoxication with quinidine. Hypotension, rapidly progressing to oliguria and shock, was resistant to the usual therapeutic interventions but responded favorably to the use of an intra-aortic balloon pump. Some hemodynamic implications are discussed. Pulmonary edema occurred and was treated with positive end- expiratory pressure. Electrocardiographic disturbances in conduction, transient bradycardia and recurrent ventricular arrhythmias characterized the initial 36-hour critical period. Unexplained electrolyte abnormalities occurred and further complicated management.


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Journal of Pharmacy PracticeHome page
D. L. Laven and L. Oller
Drug Poisoning and Overdose for the Health Professional: Review of Select Over-the-Counter (OTC) and Prescription Medications
Journal of Pharmacy Practice, February 1, 2000; 13(1): 37 - 81.
[Abstract] [PDF]




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Copyright © 1978 by the American College of Chest Physicians.