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Chest, Vol 80, 892-895, Copyright © 1981 by American College of Chest Physicians

ARTICLES

Lung mucociliary clearance in patients wit Young's syndrome

D Pavia, JE Agnew, JR Bateman, NF Sheahan, RK Knight, WF Hendry and SW Clarke

Lung mucociliary clearance was measured in 14 patients with primary obstructive azoospermia and chest involvement (Young's syndrome) using the objective, in vivo radioaerosol technique. Lung mucociliary transport was significantly reduced in patients with Young's syndrome compared to 14 control subjects matched for physical characteristics, tobacco consumption and initial topographic distribution of tracer particles within the lungs. This finding indirectly supports the hypothesis that congenital abnormality in the propulsion of sperm in the ciliated epididymis results in the absence of sperm in the ejaculate.




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Copyright © 1981 by the American College of Chest Physicians.