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Chest, Vol 84, 186-190, Copyright © 1983 by American College of Chest Physicians

ARTICLES

Rapid diagnosis of Legionnaires' disease by bronchoalveolar lavage

WR Kohorst, SA Schonfeld, JE Macklin and ME Whitcomb

Legionella pneumophila has, in recent years, emerged as a common pulmonary pathogen in the normal and immuno-compromised patient (ICP). Making a specific etiologic diagnosis of pneumonia in the latter group is a common clinical dilemma often complicated by poor specimen availability and risks of invasive procedures. Improved staining and isolation techniques for L pneumophila would suggest that early diagnosis could be possible if adequate specimens were available. This report summarizes our experience with bronchoalveolar lavage (BAL) with which we have diagnosed L pneumophila in eight immunocompromised patients, well in advance of more traditional methods. On the basis of this experience, we would advocate early BAL in the ICP as a rapid, safe, moderately sensitive and specific diagnostic test to aid in the identification of L pneumophila.


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Clin. Microbiol. Rev., April 1, 1998; 11(2): 341 - 365.
[Abstract] [Full Text] [PDF]


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Copyright © 1983 by the American College of Chest Physicians.