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Chest, Vol 84, 492-493, Copyright © 1983 by American College of Chest Physicians

ARTICLES

Additive pulmonary toxicity with melphalan and busulfan therapy

D Schallier, N Impens, F Warson, S Van Belle and G De Wasch

We report a 59-year-old patient with chronic myeloid leukemia, who developed severe interstitial lung fibrosis after short term and sequential treatment with melphalan and busulfan. The probable additive toxicity of both agents on the pulmonary tissue is discussed.


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A. D. Elias and E. J. Mark
Case 25-1997- A 60-Year-Old Man with Pulmonary Infiltrates after a Bone Marrow Transplantation
N. Engl. J. Med., August 14, 1997; 337(7): 480 - 489.
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Copyright © 1983 by the American College of Chest Physicians.