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Chest, Vol 85, 284-286, Copyright © 1984 by American College of Chest Physicians


ARTICLES

Possible recurrence of amiodarone pulmonary toxicity following corticosteroid therapy

J Joelson, J Kluger, S Cole and M Conway

Amiodarone hydrochloride, a new antiarrhythmic agent, has been associated with pulmonary toxicity characterized by cough, dyspnea and diffuse pulmonary infiltrates. We describe a case of fibrosing alveolitis, diagnosed by lung biopsy, in a patient receiving amiodarone which responded to corticosteroid therapy. The pulmonary symptoms recurred after discontinuing corticosteroids, five months after amiodarone was stopped, and were associated with a persistent amiodarone level. To our knowledge, this recurrence of amiodarone pulmonary toxicity has not been reported previously.


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