Chest ACCP Education Calendar
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Guest Access | Sign In via User Name/Password
This Article
Right arrow Full Text (PDF) Free
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Article Archive
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Guccion, J.
Right arrow Articles by Saini, N
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Guccion, J.
Right arrow Articles by Saini, N

Chest, Vol 85, 571-573, Copyright © 1984 by American College of Chest Physicians

ARTICLES

Pulmonary hyalinizing granuloma. Electron microscopic and immunologic studies

JG Guccion, PK Rohatgi and N Saini

We present a case of pulmonary hyalinizing granuloma (PHG). On light microscopy, the pulmonary nodular lesions consisted of extracellular, eosinophilic hyaline lamellae. Histochemical stains of the hyaline lamellae for amyloid were focally positive and the diagnosis of amyloidosis was seriously considered; however, on electron microscopic examination, the hyaline lamellae consisted of electrondense, compact, amorphous material quite unlike fibrillar amyloid. Although circulating immune complexes containing IgA were detected in our patient, immunoperoxidase stains did not reveal immunoglobulins in the hyaline lamellae. This case illustrates the value of electron microscopy in differentiating PHG from amyloidosis and supports the hypothesis that PHG represents an exaggerated immune response.


This article has been cited by other articles:


Home page
 Eur Respir JHome page
K.M.A. O'Reilly, J.A. Boscia, K.L. Kaplan, and P.J. Sime
A case of steroid responsive pulmonary hyalinising granuloma: complicated by deep venous thrombosis
Eur. Respir. J., June 1, 2004; 23(6): 954 - 956.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
Y. Ren, E. N. Raitz, K. R. Lee, S. K. Pingleton, and O. Tawfik
Pulmonary Small Lymphocytic Lymphoma (Mucosa-Associated Lymphoid Tissue Type) Associated With Pulmonary Hyalinizing Granuloma
Chest, September 1, 2001; 120(3): 1027 - 1030.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1984 by the American College of Chest Physicians.