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Chest, Vol 86, 20-29, Copyright © 1984 by American College of Chest Physicians

ARTICLES

Subclinical effects of smoking. Physiologic comparison of healthy middle-aged smokers and nonsmokers and interrelationships of lung function measurements

RJ Knudson, JW Bloom, DE Knudson and WT Kaltenborn

Measurements of ventilatory function, distribution of ventilation, diffusing capacity, and lung mechanics were made on healthy middle-aged smokers and nonsmokers drawn from a randomly selected population in order to assess the effects of cigarette smoking and the interrelationships of the several indices of lung function. Although very few subjects had abnormal function, there were significant differences in most indices of function between smokers and nonsmokers. For the total group studied, there were significant correlations between various indices of function. A significant proportion of the variance in diffusing capacity and in diffusing capacity per liter of lung volume can be accounted for by an index of lung recoil which may, in turn, be related to size of terminal air spaces.


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[Abstract] [Full Text] [PDF]


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Copyright © 1984 by the American College of Chest Physicians.