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Chest, Vol 86, 492-494, Copyright © 1984 by American College of Chest Physicians

ARTICLES

Exacerbation of bronchial asthma following treatment with amiodarone. Demonstration of an antiadrenergic effect in vitro

D Hunt, P Kertes, S Venables, J Callaghan and LC Harrison

We describe a patient with bronchial asthma whose respiratory symptoms worsened during treatment and rechallenge with amiodarone. Laboratory studies on cultured pulmonary cells demonstrated an anti-beta- adrenergic effect of amiodarone not due to inhibition of beta- adrenergic receptor binding. Amiodarone should be used with caution in patients with obstructive pulmonary disease.


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 The Annals of PharmacotherapyHome page
O. Yavuzgil, T. Goksel, C. Gurgun, and C. Hasdemir
New-onset bronchial asthma induced by low-dose amiodarone
Ann. Pharmacother., February 1, 2005; 39(2): 385 - 386.
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Copyright © 1984 by the American College of Chest Physicians.