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Chest, Vol 86, 704-706, Copyright © 1984 by American College of Chest Physicians


ARTICLES

Enlarged pulmonary arteriovenous vessels in COPD. Another possible mechanism of hypoxemia

WC Miller, JG Heard and KM Unger

Among 27 patients with moderate-to-severe chronic obstructive lung disease, 22 had anatomic intrapulmonary shunting greater than that seen in normal subjects. The shunted blood passed through enlarged pulmonary vessels, as demonstrated with particles 10-90 microns in diameter. The shunt magnitude was correlated with the decrement in lung diffusing capacity. It did not correlate well with pulmonary mechanical abnormalities such as air flows and volumes or resting blood gas data. Nevertheless, shunting through enlarged pulmonary vessels may play a role in the hypoxemia seen in COPD patients, especially at exercise.





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Copyright © 1984 by the American College of Chest Physicians.