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Chest, Vol 88, 143-145, Copyright © 1985 by American College of Chest Physicians

ARTICLES

Amiodarone pulmonary toxicity. Chest radiography and CT in asymptomatic patients

CG Standertskjold-Nordenstam, JC Wandtke, WB Hood Jr, FT Zugibe and L Butler

Two asymptomatic patients from a group of 30 being treated with the antiarrhythmic drug amiodarone developed roentgenographic pulmonary and pleural reactions. Computed tomography in one patient with an uncommon radiographic pattern of fuzzy nodules showed the spatial distribution of the parenchymal changes, as well as unrecognized pleural thickening. The disease in these asymptomatic patients was presumably detected on the periodic chest roentgenogram at an early stage because the changes disappeared after withdrawal of the drug. Periodic chest radiographs are recommended during amiodarone therapy and CT may be useful in evaluation of patients with unusual chest radiographic findings.


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Copyright © 1985 by the American College of Chest Physicians.