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Chest, Vol 88, 466-467, Copyright © 1985 by American College of Chest Physicians

ARTICLES

A pseudoepidemic of Legionella infections

RL Ristagno and LD Saravolatz

During a six-month period, we observed an increase in the incidence of presumed Legionnaires' disease (LD) due to false-positive direct immunofluorescent antibody (DFA) staining. Contamination of the DFA staining reagents with Legionella appeared to account for our pseudoepidemic. Although a positive DFA stain has been regarded as highly specific for the diagnosis of LD, the clinician must interpret such results with caution.




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Copyright © 1985 by the American College of Chest Physicians.