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Chest, Vol 88, 207S-209S, Copyright © 1985 by American College of Chest Physicians

ARTICLES

Peptides, endothelium, and pulmonary vascular reactivity [published erratum appears in Chest 1986 Sep;90(3):468]

SI Said

The lung contains a number of active peptides that can influence endothelial and smooth muscle function. At least two of these peptides are metabolized by endothelium, and endothelium is required for the vasodilator action of several peptides. A vasodilator peptide, VIP, may be the transmitter of the nonadrenergic, noncholinergic system, the major component of neurogenic relaxation of pulmonary vessels.




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Copyright © 1985 by the American College of Chest Physicians.