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(Chest. 1985;88:220S-223S.)
© 1985 American College of Chest Physicians

Calcium Kinetics in Vascular Smooth Muscle

George B. Weiss Ph.D.1

1 Research Department, Pharmaceuticals Division, Ciba-Geigy Corporation, Summit, N.J.

The accumulation, binding, and mobilization of Ca++ in vascular smooth muscle directly affects intracellular free Ca++ levels and contractility. Techniques have been developed to delineate Ca++ uptake and efflux parameters in isolated vessels. Similar Ca++-related components are present in different types of vessels, but their relative importance for induction and maintenance of tension differ.






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Copyright © 1985 by the American College of Chest Physicians.