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Chest, Vol 89, 894-895, Copyright © 1986 by American College of Chest Physicians

ARTICLES

Danger of vasodilator therapy for pulmonary hypertension in patent foramen ovale

JF Laine, M Slama, P Petitpretz, P Girard and G Motte

A 23-year-old woman with systemic lupus erythematosus was found to have severe pulmonary hypertension with secondary patency of the foramen ovale. Infusion of hydralazine increased the basal right-to-left shunt and resulted in a dramatic fall in arterial oxygen pressure, with subsequent irreversible cardiovascular collapse. Vasodilator therapy appears to be hazardous in patients with severe pulmonary hypertension and patent foramen ovale.


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 Asian Cardiovasc. Thorac. Ann.Home page
H. Sharif, A T. Pezzella, H. H Farah, R. Baljepally, and D. Maki
Intracardiac Right-to-Left Shunt Complicating Right Ventricular Failure
Asian Cardiovasc Thorac Ann, December 1, 1999; 7(4): 287 - 291.
[Abstract] [Full Text] [PDF]


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Copyright © 1986 by the American College of Chest Physicians.