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Chest, Vol 90, 489-493, Copyright © 1986 by American College of Chest Physicians

ARTICLES

Double-blind crossover study of five bronchodilator medications and two delivery methods in stable asthma. Is there a best combination for use in the pulmonary laboratory?

JH Cissik, FR Bode and JA Smith

The effects of five bronchodilator drugs and two methods of delivery (nebulizer vs metered-dose inhalers) on pulmonary function were studied in ten subjects with stable asthma. All subjects demonstrated statistically significant improvements (p less than 0.05) in pulmonary function relative to baseline and placebo effects after each medication, regardless of method of delivery; however, there was no statistically significant difference between the changes in pulmonary function caused by medication, method, or medication-method combination (p greater than 0.05). The choice of medication and device for delivery would appear to depend on the budget and time available in the laboratory.


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 Qual Saf Health CareHome page
J Wright, D Brocklebank, and F Ram
Inhaler devices for the treatment of asthma and chronic obstructive airways disease (COPD)
Qual. Saf. Health Care, January 12, 2002; 11(4): 376 - 382.
[Abstract] [Full Text] [PDF]


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Copyright © 1986 by the American College of Chest Physicians.