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Chest, Vol 91, 403-407, Copyright © 1987 by American College of Chest Physicians

ARTICLES

Parotid gland biopsy and 67Ga imaging correlation in systemic sarcoidosis

SD Brantley, JA Orzel, FL Weiland and JH Bower

We correlated the results of parotid gland biopsy, chest roentgenograms, and gallium citrate scintigraphy in 24 patients evaluated for possible systemic sarcoidosis. Of 19 patients ultimately proven to have sarcoidosis, 11 (57.9 percent) had positive parotid gland biopsy. The yield of parotid gland biopsy in patients with abnormal gallium parotid activity was only marginally higher (64.7 percent). Abnormal parotid gland uptake of gallium citrate was seen in 17 of these 19 patients (89.5 percent) and was always associated with abnormal lung or perihilar activity. The parotid gland biopsy is a useful technique for obtaining the tissue diagnosis of sarcoidosis; however, gallium scintigraphy should not be performed to select patients as this will only marginally increase the biopsy yield.




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Copyright © 1987 by the American College of Chest Physicians.