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Chest, Vol 91, 620-621, Copyright © 1987 by American College of Chest Physicians

ARTICLES

Severe febrile reaction to isoniazid

NY Gabrail

A case of severe febrile reaction to INH is described. The patient had a mild febrile reaction two weeks following INH prophylaxis. Isoniazid was discontinued. Two weeks later and on rechallenge with INH she developed a severe febrile reaction with protracted hypotension. An initial mild febrile reaction to INH is a warning sign that rechallenge can result in a life-threatening situation.




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Copyright © 1987 by the American College of Chest Physicians.