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Chest, Vol 91, 148S-151S, Copyright © 1987 by American College of Chest Physicians

REVIEWS

Metabolic basis of asthma. A united hypothesis

KP Agrawal

Asthma is a heterogenous disease triggered by a large number of different stimuli. This article presents a theory of the metabolic mechanisms of asthma. The theory is based on the growing understanding of the activity of lysophosphatidylcholine (LPC). Since the effect of LPC on cell membranes, membrane bound enzymes and the various types of cells involved in the pathogenesis of asthma, this may represent a unifying link between the various types of asthma.




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Copyright © 1987 by the American College of Chest Physicians.