Chest, Vol 91, 833-836, Copyright © 1987 by American College of Chest Physicians

ARTICLES

Breathing pattern abnormalities and arterial oxygen desaturation during sleep in the congestive heart failure syndrome. Improvement following medical therapy

DS Dark, SK Pingleton, GR Kerby, JE Crabb, SB Gollub, TR Glatter and MI Dunn

We observed breathing pattern abnormalities and arterial oxygen desaturation in patients with stable congestive heart failure during overnight polysomnography. To determine whether congestive heart failure was the reason for these abnormalities, we then studied six additional patients before and after treatment of heart failure. Breathing was more abnormal (153 +/- 87 episodes/night) during decompensation of heart failure and improved with medical therapy (72 +/- 100 episodes/night) (p less than 0.05). Abnormal breathing patterns resolved in three patients, improved in two, and were unchanged in one patient after therapy. Allographic cardiac transplantation in one patient whose sleep study remained unchanged after medical therapy was associated with resolution of breathing pattern abnormalities and severe desaturation during sleep. Therapy-related improvement in nocturnal respiratory events suggests congestive heart failure is a contributing factor for breathing abnormalities and arterial oxygen desaturation during sleep.

This article has been cited by other articles:

				T. Kara, M. Novak, J. Nykodym, K. A. Bybee, J. Meluzin, M. Orban, Z. Novakova, J. Lipoldova, D. L. Hayes, M. Soucek, et al. Short-term Effects of Cardiac Resynchronization Therapy on Sleep-Disordered Breathing in Patients With Systolic Heart Failure Chest, July 1, 2008; 134(1): 87 - 93. [Abstract] [Full Text] [PDF]

				A. Garcia-Touchard, V. K. Somers, L. J. Olson, and S. M. Caples Central Sleep Apnea: Implications for Congestive Heart Failure Chest, June 1, 2008; 133(6): 1495 - 1504. [Abstract] [Full Text] [PDF]

				M. Arzt and T. D. Bradley Treatment of Sleep Apnea in Heart Failure Am. J. Respir. Crit. Care Med., June 15, 2006; 173(12): 1300 - 1308. [Abstract] [Full Text] [PDF]

				K. Ferrier, A. Campbell, B. Yee, M. Richards, T. O'Meeghan, M. Weatherall, and A. Neill Sleep-Disordered Breathing Occurs Frequently in Stable Outpatients With Congestive Heart Failure Chest, October 1, 2005; 128(4): 2116 - 2122. [Abstract] [Full Text] [PDF]

				R. S. T. LEUNG and T. DOUGLAS BRADLEY Sleep Apnea and Cardiovascular Disease Am. J. Respir. Crit. Care Med., December 15, 2001; 164(12): 2147 - 2165. [Full Text] [PDF]

				T. MOOE, K. A. FRANKLIN, K. HOLMSTROM, T. RABBEN, and U. WIKLUND Sleep-disordered Breathing and Coronary Artery Disease . Long-term Prognosis Am. J. Respir. Crit. Care Med., November 15, 2001; 164(10): 1910 - 1913. [Abstract] [Full Text] [PDF]

				S. L. Krachman, G. E. D’Alonzo, T. J. Berger, and H. J. Eisen Comparison of Oxygen Therapy With Nasal Continuous Positive Airway Pressure on Cheyne-Stokes Respiration During Sleep in Congestive Heart Failure* Chest, December 1, 1999; 116(6): 1550 - 1557. [Abstract] [Full Text] [PDF]

				F. Tremel, J.-L. Pepin, D. Veale, B. Wuyam, J.-P. Siche, J.M. Mallion, and P. Levy High prevalence and persistence of sleep apnoea in patients referred for acute left ventricular failure and medically treated over 2 months Eur. Heart J., August 2, 1999; 20(16): 1201 - 1209. [Abstract] [PDF]

				M T Naughton Pathophysiology and treatment of Cheyne-Stokes respiration Thorax, June 1, 1998; 53(6): 514 - 518. [Full Text]

				J. Tomcsanyi, K. Karlocai, and L. Papp Disappearance of periodic breathing after heart operations J. Thorac. Cardiovasc. Surg., January 1, 1994; 107(1): 317 - 317. [Full Text]