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(Chest. 1988;93:217-219.)
© 1988 American College of Chest Physicians

Naloxone and Naltrexone

Application in COPD

Stan B. Reents Pharm.D.1 and Charles A. Beck Jr. M.D.1

1 From Ingalls Memorial Hospital, Harvey, Illinois

The narcotic antagonists naloxone and naltrexone were used as respiratory stimulants in two patients failing traditional medical therapy for COPD. Both patients demonstrated improvement while receiving the drugs, but developed respiratory failure when they were discontinued abruptly. In selected patients with COPD, narcotic antagonists may offer an additional mode of therapy.






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Copyright © 1988 by the American College of Chest Physicians.