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Chest, Vol 93, 1196-1198, Copyright © 1988 by American College of Chest Physicians

ARTICLES

Malignant pleural effusion treated by tetracycline sclerotherapy. A comparison of single vs repeated instillation

L Landvater, WR Hix, M Mills, RS Siegel and BL Aaron
Division of Cardiothoracic Surgery, George Washington University Medical Center, Washington, DC.

Fifty patients with malignant pleural effusion were randomized to receive one or two doses of tetracycline sclerotherapy. We found that a single sclerotherapy treatment with tetracycline at a dose of 20 mg/kg was as effective as two sclerotherapy treatments and provided symptomatic relief in 46 of the 50 patients.


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