Chest ACCP Career Connection
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Guest Access | Sign In via User Name/Password
This Article
Right arrow Full Text (PDF) Free
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Article Archive
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by van Zyl, A.
Right arrow Articles by Opie, L.
Right arrow Search for Related Content
PubMed
Right arrow Articles by van Zyl, A.
Right arrow Articles by Opie, L.

Chest, Vol 95, 209-213, Copyright © 1989 by American College of Chest Physicians

ARTICLES

Comparison of respiratory effects of two cardioselective beta-blockers, celiprolol and atenolol, in asthmatics with mild to moderate hypertension

AI van Zyl, AA Jennings, ED Bateman and LH Opie
Ischaemic Heart Disease Research Unit, University of Cape Town, South Africa.

The effects of two cardioselective beta-adrenergic blocking agents-- celiprolol (claimed to have bronchodilator properties) and atenolol (without such claims)--on respiratory function and control of asthma were studied in ten asthmatic patients with mild to moderate essential hypertension. Following a beta-2 agonist-free period of ten hours, administration of 100 mg of atenolol was associated with bronchoconstriction (p less than 0.05), whereas 400 mg of celiprolol was not. Responsiveness to beta-2 agonist therapy was retained with both agents (p less than 0.05). Day-to-day asthma control, interpreted from patient recordings of peak flow, inhaler use and symptom scores, were all no different on either agent from placebo. When given acutely, celiprolol appeared to have acute bronchosparing properties, possibly providing a greater margin of respiratory safety than atenolol.


This article has been cited by other articles:


Home page
 ANN INTERN MEDHome page
S. R. Salpeter, T. M. Ormiston, and E. E. Salpeter
Cardioselective {beta}-Blockers in Patients with Reactive Airway Disease: A Meta-Analysis
Ann Intern Med, November 5, 2002; 137(9): 715 - 725.
[Abstract] [Full Text] [PDF]

Home page
 Canadian J. AnesthesiaHome page
V. Piriou, A. Aouifi, and J.J. Lehot
Interet des beta-bloquants en medecine perioperatoire. Premiere partie: notions fondamentales
Can J Anesth, July 1, 2000; 47(7): 653 - 663.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1989 by the American College of Chest Physicians.