Chest, Vol 95, 320-324, Copyright © 1989 by American College of Chest Physicians

ARTICLES

Survival time of patients with pleural metastatic carcinoma predicted by glucose and pH studies

F Rodriguez-Panadero and J Lopez-Mejias
Pneumology Service, Virgen del Rocio Hospital, Seville, Spain.

STUDY OBJECTIVE: To determine the survival time of patients with pleural metastatic carcinoma diagnosed by thoracoscopy, as related to the pleural glucose and pH levels, and to the extension of pleural neoplastic lesions. DESIGN: Cohort analytic prospective study. Follow- up of the patients from diagnostic thoracoscopy to death (range: one to 29 months). SETTING: Referral Pneumology Service at a Tertiary Care Center. PATIENTS: Consecutive sample of 50 patients with pleural metastatic carcinoma diagnosed by thoracoscopy. Three patients were lost in the follow-up. INTERVENTIONS: Talc pleurodesis was performed after diagnosis and with the same technique in every case. MEASUREMENTS AND RESULTS: In all the cases, the extension of the tumorous lesions was determined by thoracoscopy (classified on a scale from 0 to 9) and the survival time was studied from the time that thoracoscopic diagnosis was made. On the same or the previous day as the exploration, blood and pleural fluid glucose levels as well as arterial and pleural pH and gas tensions were determined.

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