Chest Email Content Delivery
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Guest Access | Sign In via User Name/Password
This Article
Right arrow Full Text (PDF) Free
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Article Archive
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Meltzer, A. A.
Right arrow Articles by Scott, P. H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Meltzer, A. A.
Right arrow Articles by Scott, P. H.

Chest, Vol 96, 329-333, Copyright © 1989 by American College of Chest Physicians

ARTICLES

An assessment of peak expiratory flow as a surrogate measurement of FEV1 in stable asthmatic children

AA Meltzer, MH Smolensky, GE D'Alonzo, RB Harrist and PH Scott
University of Texas School of Public Health, Houston 77030.

We examined the relationship over 24 hours between percent-predicted values (PPV) of peak expiratory flow (PEF) and forced expiratory volume in one second (FEV1) in a group of 23 stable untreated asthmatic children 6 to 17 years of age by means of regression analysis as well as the percentage difference between the PPV of these two measurements. Although the Pearson correlation coefficient between the PPV was consistently high, ranging between 0.854 and 0.892, the assumption that such a finding substantiates the substitution of PEF for FEV1 is called into question. Over 50 percent of the subjects displayed a 10 percent or greater difference in the PPV between the two measurements, regardless of the time of day the two respiratory variable were determined, while over one-third of all subjects evidenced a 20 percent or greater discrepancy between the PPV of the two measures. While, on a group basis, there was no statistically significant difference in the mean percentage difference over 24 hours between the PPV of FEV1, when compared with the corresponding measurement of PEF, reliance on PEF alone in individual subjects may result in a false impression of the patency of the airways in comparison to the FEV1.


This article has been cited by other articles:


Home page
 ChestHome page
M. J. Hegewald, M. J. Lefor, R. L. Jensen, R. O. Crapo, S. B. Kritchevsky, C. L. Haggerty, D. C. Bauer, S. Satterfield, T. Harris, and for the Health, Aging, and Body Composition Study
Peak Expiratory Flow Is Not a Quality Indicator for Spirometry: Peak Expiratory Flow Variability and FEV1 Are Poorly Correlated in an Elderly Population
Chest, May 1, 2007; 131(5): 1494 - 1499.
[Abstract] [Full Text] [PDF]

Home page
 Arch Pediatr Adolesc MedHome page
J. W. Stout, C. M. Visness, P. Enright, C. Lamm, G. Shapiro, V. N. Gan, G. K. Adams III, and H. E. Mitchell
Classification of Asthma Severity in Children: The Contribution of Pulmonary Function Testing
Arch Pediatr Adolesc Med, August 1, 2006; 160(8): 844 - 850.
[Abstract] [Full Text] [PDF]

Home page
 Arch Pediatr Adolesc MedHome page
S. Guendelman, K. Meade, M. Benson, Y. Q. Chen, and S. Samuels
Improving Asthma Outcomes and Self-management Behaviors of Inner-city Children: A Randomized Trial of the Health Buddy Interactive Device and an Asthma Diary
Arch Pediatr Adolesc Med, February 1, 2002; 156(2): 114 - 120.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
S. Goldberg, C. Springer, A. Avital, S. Godfrey, and E. Bar-Yishay
Can Peak Expiratory Flow Measurements Estimate Small Airway Function in Asthmatic Children?
Chest, August 1, 2001; 120(2): 482 - 488.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
R. Crapo
Guidelines for Methacholine and Exercise Challenge Testing---1999 . THIS OFFICIAL STATEMENT OF THE AMERICAN THORACIC SOCIETY WAS ADOPTED BY THE ATS BOARD OF DIRECTORS, JULY 1999
Am. J. Respir. Crit. Care Med., January 1, 2000; 161(1): 309 - 329.
[Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1989 by the American College of Chest Physicians.