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Chest, Vol 96, 1199-1200, Copyright © 1989 by American College of Chest Physicians

ARTICLES

Intravascular lymphomatosis (malignant angioendotheliomatosis) presenting as pulmonary hypertension

LS Snyder, KR Harmon and RD Estensen
Department of Medicine, University of Minnesota Medical School, Minneapolis 55455.

Intravascular lymphomatosis is a rare lymphoma characterized by proliferation of malignant cells within the lumen of small blood vessels. We describe a case of intravascular lymphomatosis resulting in pulmonary hypertension, hypoxemia, and dyspnea. This lymphoma occasionally responds to combination chemotherapy, suggesting that pulmonary hypertension secondary to intravascular lymphomatosis may be reversible. Intravascular lymphomatosis should be considered in the differential diagnosis of pulmonary hypertension.


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